Thursday, November 12, 2009

Researchers have found a crucial genetic difference between humans and chimps that could help explain our language and speech abilities. The difference lies in a gene called FOXP2 which encodes for a protein of the same name. This acts as a transcription factor, controlling the activity of other genes.

The human and chimp versions of the protein differ in only two of their 740 amino acid components, but when researchers at the University of California, Los Angeles, replaced the human gene with the chimp version in neurons grown in the laboratory, they found it affected the expression of at least 116 other genes.

The results are detailed in a paper published on Thursday in the scientific journal Nature.

Author of the study Dr. Daniel Geschwind, of the David Geffen School of Medicine at UCLA, said the gene had a “major role” in differences between chimps and humans. “We showed that the human and chimp versions of FOXP2 not only look different but function differently too.”

Some of the affected genes control the formation of connections in the brain, whilst others relate to facial movements. Several have already been found to be involved in language disorders. Mutations in FOXP2 itself were also known to affect speech and language; the gene was first identified in members of a family suffering from language problems who were found to share a genetic mutation.

Frances Vargha-Khadem at University College London has studied patients with FOXP2 mutations, and agrees with the new research. As well as language problems, some of her subjects have changes in the shape of their jaws, mouths and tongues. She thinks that chimps may also have these differences.

“We believe FOXP2 is not only important for the higher order cognitive aspect of language but also for the motor aspect of speech and language,” said Genevieve Konopka, one of the authors of the paper at UCLA.

Previous research indicates that the changes in FOXP2 occurred around 200,000 years ago with the rise of modern humans. Geschwind also suggests that several of the related genes may have evolved together. Preliminary studies have shown signs that they too emerged relatively recently.

Scientists are now keen to further study FOXP2 and the genes that it affects. Geschwind believes this could eventually lead to breakthroughs in treatment for disorders such as autism and schizophrenia, which affect language skills.

The study was funded by the National Institute of Mental Health, the A.P. Giannini Foundation and the National Alliance for Research on Schizophrenia and Depression.

Monday, June 2, 2008

A Texas court has announced that all children taken from the Fundamentalist Church of Jesus Christ of Latter-Day Saints (FLDS) compound in Texas are being returned to their parents. Beginning today, parents have been allowed to collect their children, all of whom were in state custody before the announcement.

The more than 460 allegedly abused children were taken into state custody last month after officials say they received a call from a distressed 16-year old girl. The children were found in a 1700-acre compound belonging to the FLDS. It is now believed that the original phone call was actually a hoax.

The decision follows an appeals court ruling that Texas Child Protective Services (CPS) should not have taken the children from the FLDS.

Recently the CPS in Texas filed papers on this issue, saying that the families may choose to flee Texas if they are reunited per the appeals courts ruling. If the families were to do that, they would then be outside the court’s jurisdiction, putting the children at risk of abuse.

The CPS in Texas released a statement regarding the court ruling: “We are disappointed, but we understand and respect the court’s decision and will take immediate steps to comply. Child Protective Services has one purpose in this case – to protect the children. Our goal is to reunite families whenever we can do so and make sure the children will be safe. We will continue to prepare for the prompt and orderly reunification of these children with their families. We also will work with the district court to ensure the safety of the children and that all of our actions conform with the decision of the Texas Supreme Court.”

Friday, September 9, 2005

New Orleans, Louisiana —After Category 4 storm Hurricane Katrina slammed into New Orleans, on the night before August 29, 2005, several flood control constructions failed. Much of the city flooded through the openings. One of these was the flood wall forming one side of the 17th Street Canal, near Lake Pontchartrain. The U.S. Army Corps of Engineers (USACE) is the primary agency for engineering support during such emergencies. A USACE team was assessing the situation in New Orleans on the 29th, water flow was stopped September 2nd, and the breach was closed on September 5th.

Friday, August 25, 2006

Israel has purchased two more Dolphin class submarines which have the capacity to carry nuclear warheads. Israel already has three older nuclear weapons-capable Dolphin submarines but the new Dolphins have propulsion systems that allow them to remain submerged for longer periods of time, according to the Jerusalem Post, making it harder for them to be tracked by satellite. Experts view the purchase as a clear signal to Iran that Israel can retaliate if subjected to a nuclear attack.

“The Iranians would be very foolish if they attacked Israel,” said Paul Beaver, a British based defence analyst, speaking to the Washington Post. According to Beaver, the submarines would provide Israel with both first strike and second strike capability.

Israel already has land-based nuclear-capable ballistic missiles in the form of the Jericho I and II missiles.

German officials confirm that the contracts for the new submarines was signed July 6. The Jerusalem Post reports that they will be operational shortly.

Israel has never confirmed nor denied that it has nuclear weapons but is believed to have the world’s sixth largest stockpile of the devices, with most outside estimates putting their stockpile in the low hundreds. Israel’s possession of nuclear arms has often been a locus of bitter controversy in the Middle East, especially among countries who believe that the world community, and especially the United States, is hypocritical in its tolerance of Israeli nuclear arms while decrying the efforts of other Middle Eastern nations to develop their own nuclear capabilities.

Meanwhile, the Jerusalem Post reports there is a growing mood among Israel’s defence establishment that the country will have to act independently to stop Iran from obtaining nuclear weapons as the United States is unlikely to do so.

“America is stuck in Iraq and cannot go after Iran militarily right now,” according to an unnamed official quoted by the paper.

A report by the US House of Representatives’ Intelligence Committee released on Wednesday asserts that if Iran arms itself with nuclear weapons, Israel would be pressed to respond militarily. “A nuclear armed Iran would likely exacerbate regional tensions. Israel would find it hard to live with a nuclear armed Iran and could take military action against Iranian nuclear facilities,” the report states. Iran has continually maintained that it seeks only to develop nuclear technology for the production of electrical power, though this has been disputed by many nations.

Wednesday, October 21, 2015

The Recorder of London, His Honour Judge Nicholas Hilliard QC, today set a provisional timetable in the case against Stephen Port, an alleged serial killer. January 9 was set for a plea and case management hearing. The trial has been scheduled for April 2016, and is currently expected to last four weeks.

Port, 40, attended the hearing from HMP Pentonville via videolink. He spent the ten-minute hearing looking down, and spoke only to confirm his identity. He wore a bright yellow and green prison-issued uniform designed to make him highly visible should he escape.

Port faces four counts of murder and four counts of “administering a poison with intent to endanger life or inflict grievous bodily harm”. He is alleged to have given overdoses of recreational drug GHB. He allegedly murdered the men at his home before dumping the bodies, after finding victims online using gay dating services.

He was charged on Sunday. On Monday he appeared before a Magistrates’ Court which sent the case to today’s hearing at the famed Old Bailey courthouse. Port has not applied for bail and remains in custody.

The Metropolitan Police has referred itself to the Independent Police Complaints Commission concerning what police called “potential vulnerabilities in [our response] to the four deaths.” Police only linked the deaths a week ago on Wednesday, when they were passed to serious crime investigators.

Three of the deaths occurred last year. Anthony Patrick Walgate, 23, was found dead on June 19, 2014 in Cooke Street. Port lives in Cooke Street. The other three alleged victims were found in the vicinity of St. Margaret’s Church on North Street. Gabriel Kovari, 22, was discovered dead on August 28. Daniel Whitworth, 21, was found dead the following month on September 20. Fourth alleged victim Jack Taylor, 25, was found a year later on September 14.

Whitworth and Kovari were known to each other, according to testimony at the inquest.

Port was arrested following a police appeal to trace a man seen with Taylor shortly before his death. Police at the time released security footage of Taylor’s movements, with an officer telling the press “the man captured on CCTV may well be the last person to talk to Jack.”

Wednesday, March 2, 2005

Bucharest, Romania — The city centre of Bucharest, the capital of Romania, is set to get a major facelift due to a real estate project called Esplanada (The Esplanade), which will be constructed by TriGranit Development Corporation. The total investment in the project will be greater than 800 million euro and aims to build a modern commercial pedestrian area in downtown Bucharest, with several shopping malls, office buildings, hotels and dwellings. It will be the largest real estate program in Romania since the fall of Communism in 1989.

Bucharest is currently looking at possibilities to improve its appearance and rebrand itself as a lively, creative and vibrant city. Many initiatives have sprung up to improve the city, including the organisation of CowParade later this year. Additionally, the old town centre will be restored. Due to Romania’s current economic boom, several other major construction projects are taking place.

Bucharest City Hall has blocked traffic in the city center due both to the old town restoration and to the Esplanada project.

Monday, February 11, 2008

A spacewalk was conducted today by astronauts Rex Walheim and Stan Love, members of the STS-122 Space Shuttle crew, to install the new Columbus module onto the International Space Station.

The spacewalk, or extra-vehicular activity (EVA), began at 14:13 UTC, with the astronauts leaving the Quest airlock of the Space Station, and starting work to install an attachment point on top of the Columbus module, to allow it to be moved by the Station’s robotic arm. This was completed at 19:00, about an hour later than planned, owing to the installation taking longer than expected. Columbus was lifted out of the payload bay of Atlantis at 19:55 UTC, by the Space Station’s robotic arm, Canadarm2. Astronaut Dan Tani, controlling Canadarm2 from aboard the ISS remarked “Columbus has started its trip to the new world”. At 21:29, Columbus soft-docked with the Space Station’s Harmony node, and the module finished bolting itself in place by 21:44.

Meanwhile, the astronauts performed some tasks to prepare for the next spacewalk, which is currently scheduled for Wednesday. They loosened bolts holding a nitrogen tank in place on the port truss segment of the Station, ahead of its replacement. It was originally planned that they would also disconnect pipes and electrical connections, however these objectives were delayed to Wednesday’s spacewalk, due to time constraints. The EVA finished at 22:12 UTC, having lasted seven hours and fifty-eight minutes

This marks the 102^nd spacewalk as part of the International Space Station programme, and the first of three planned for the STS-122 Shuttle mission. It was originally planned that German astronaut Hans Schlegel would perform the EVA instead of Stan Love, however he was unable to do so due to an undisclosed medical problem.

Thursday, February 23, 2006

Buffalo, New York —

Residents and business owners in the Elmwood Avenue neighborhood and surrounding area in Buffalo heard a competing proposal for development in their neighborhood at the February 22 meeting held at the Burchfield-Penney Art Gallery, at Buffalo State College. The meeting, attended by at least 140, was originally to consider the Elmwood Village Hotel but also included a new revitalization proposal from Rocco Termini which would increase retail space, but involves less demolition and no hotel.

Rocco Termini, a Buffalo, New York developer wants to develop the corner of Elmwood and Forest, the same spot where Savarino Construction Services Corporation want to build the Elmwood Village Hotel.

Termini proposed that a similar revitalization take place on the intersection like one that incorporated 3 buildings on Aurburn and Elmwood just last year. Termini’s proposal will add more retail space than Savarino’s proposal with the possibility of including up to seven retail outlets.

“I just think it’s necessary to preserve the streetscape that we have. That’s the whole point of living and shopping on Elmwood,” said Termini. “You should be able to go into little shops, that have unique items, and that bring people to Elmwood. When you bring a big box on Elmwood Avenue, it takes something away from the urban-streetscape, just as suburban areas do not want a big box Wal-Mart. We don’t want a big box on Elmwood avenue and I think that’s just what this (the hotel) does, brings a big box to Elmwood,” said Termini.

When asked if there were any development companies currently interested in his proposal Termini said, “I will be willing to take a look at this myself,” said Termini. “Or I would be more than happy to be partners with Sam, Sam Savarino,” who is President and Chief Executive Officer of Savarino Construction Services Corp.

An unnamed source close to the project stated, “Rocco has serious concerns that the Mobius’s asking price could make his project infeasible.”

It is unknown if Savarino Construction or the city of Buffalo will consider Termini’s proposal.

Termini purchased and developed several buildings and areas including the Ellicott Lofts on Ellicott Street in Buffalo, which opened in 2003, The Oak School Lofts which used to be a Buffalo Alternative School, and ‘IS’ Lofts on Oak Street in Buffalo.

Eva Hassett, Vice President of Savarino Construction, and Karl Frizlen an architect from The Frizlen Group and designer of the hotel commented on the development proposal. Hassett said, “We’ve been thinking about it and trying to put it together for the last few months, and it was made public a couple of weeks ago.”

“There are lots of different areas you can look at. This is an Elmwood Avenue hotel. Putting it somewhere else makes a completely different kind of hotel. We wanted a hotel that people could walk to from the business on Elmwood. We wanted a hotel that people could walk to from the Albright Knox Art Gallery. This is really a location for this kind of hotel. Other locations end up being for other kinds of hotels,” said Hassett

“We are excited about the concept of a boutique hotel at this corner. We think it makes sense to the various businesses in the area or the galleries just down the street. We also believe that this is a way for the visitors of Buffalo to experience what the best of what Buffalo has to offer. We think it will be a great way for people from out of town, to get to know what we know about the city,” said Hassett.

Although Hassett had said that the proposal has only been around “for a few months”, Karl Frizlen said that he came up with the idea “three years ago when Hans Mobius,” former owner of the properties at risk, “came to me and asked what we could do with these properties.” Frizlen also said that he introduced Mobius to “four different developers, who after seeing the properties, did not want to tackle them, saying that they felt like it was too much for them to take on.”

Hans Mobius did not attend last nights meeting.

Frizlen is also designing the former telephone company building at 504 Elmwood which would be a “mixed use building with retail on the lowest level and lofts on the other two floors.”

After speeches from developers, residents and business owners were invited to present questions and comments.

Mark Freelend, a Buffalo resident, and local artist, said “I’m looking at my house in the picture, and I’m picturing all the houses on Granger street behind me, and I’m realizing that, if this is implemented (the hotel), we will get zero sunlight. The Sun is supposed to be free, for everyone. The people on Granger are going to have eighty windows looking at them and their children being raised, and playing in the backyard, guests looking in the windows of their houses twenty-four hours a day. A million people starring into their houses. No sunlight, and they are on permanent reality TV. Put a price on that!”

“I think this hotel is totally out of scale to the area and it does not conform to the style (of Elmwood) at all. It will totally obscure the gateway of Elmwood. The gateway now has open arms that allow for passage and view into the commercial corridor. This hotel stands as a brick wall as far as I can tell,” said Nancy Pollina one of the owners of Don Apparel at 1119 Elmwood. Pollina referenced to the recent ‘revitalization’ project on Auburn and Elmwood saying, “That building was boarded up for years, and that was beautiful a renovation. That building was not in any less need of repair than Hans Mobius’s properties.”

Both residents and business owners in the area are concerned that the proposal is moving too quickly and said that the developers should wait before having any city meetings and wait for a consensus from the community on the hotel.

Mrs. Pollina said, “I think people feel passionate about their neighborhood, and this is their neighborhood. I feel that what was most shocking is that the city’s planning board meeting and Common Council meeting, which are they need to push this through, is next week without almost no notice. This (the proposal) is being rushed.

However; Sam Savarino did say that “some people have gotten emotional about this project. And I want to let the community know that we will listen to what you have to say. We’re not forcing this down anybody’s throat. If this is not something this community wants, we do not want to have it here.”

The city’s Planning Board is expected to meet on February 28, 2006 at 8:00am in room 901 on the 9th floor of City Hall. The city’s Legislative Committee meeting of Common Council is expected to take place on the same day at 2:00pm in Council Chambers on the 13th floor of City Hall.

It has just been confirmed from an unnamed source close to the project that “significant changes” will be made to the design of the Elmwood Village Hotel. “Its not being cancelled, just redesigned,” he said. The changes are not yet known, but they are could be released “tomorrow. He (Savarino) doesn’t want it released until he touches base with a few people today.”

Thursday, January 11, 2018

On Tuesday, the first major rain storm of the year in Southern California led to flooding that has caused at least fifteen deaths, mainly in Santa Barbara County. The flooding was exacerbated by last month’s wildfires; particularly hard-hit was the wealthy community of Montecito, downstream of the site of the Thomas Fire, where at least six houses were destroyed. More than 160 people have been hospitalized, four in critical condition.

According to the United States National Weather Service, five and a half inches of rain has fallen over two days in parts of Ventura County, and more than four inches in parts of Santa Barbara County. In areas burned by the wildfires, ground cover that would have reduced runoff had been destroyed, and an impermeable layer of ash and burned soil had been created. As a result, torrents of mud ran downhill and inundated places such as Montecito. Mike Eliason, a spokesman for the Santa Barbara County Fire Department, said homes in the wealthy community had been “wiped away from their foundations” by mudflows, which also burst a gas main, leading to a fire that destroyed another building.

Sections of the 101 freeway were closed by flooding; a driver told television station KTLA that mud came “out of nowhere” and covered the highway in “about five seconds” and that he was glad he was still alive. James Cook, the Los Angeles correspondent for BBC News, reported that roads were being blocked by “boulders the size of small cars” which had tumbled down the hills. BBC also reported, 300 people had been trapped in Romero Canyon. Bill Brown, the Sheriff of Santa Barbara County, said at mid-afternoon that the number of deaths had reached thirteen and might rise. He described the flood-ravaged areas as looking “like a World War I battlefield” and said that emergency dispatchers had fielded some 600 calls between 3:00 and 6:00 am.

Emergency services including the Ventura County Aviation Unit were kept busy rescuing people. The Coast Guard sent aircraft to assist. Spokesmen reported fifty people had been rescued in each of Los Angeles and Santa Barbara Counties. Montecito resident, Berkeley Johnson, told the Santa Barbara Independent that he and his wife had taken refuge on the roof of their house but climbed came down when they heard a child crying. With a fireman’s help were able to dig out a two-year-old girl, who looked like a “muddy doll” according to Johnson.

Officials issued evacuation orders on Monday for thousands of people living in Santa Barbara, Los Angeles, and Ventura counties, but Montecito was under only voluntary evacuation. Some of the evacuation orders were lifted later on Tuesday as the rain became lighter.